Grouppe Kurosawa Medical/Biotech Gossip Blog

The Beginning of the End for the Biotech Giant Genentech. Part One

When I was in graduate school at Berkeley in the 1980s, everyone who didn't want a job in academia wanted to work for Genentech. Genentech was the first biotech company and certainly the most respected. Well, that was then and this is now.

Genentech sells two monoclonal antibody based drugs that I think are total crap. There are many people who disagree, but I couldn't care less. These two drugs, Herceptin and Avastin, are incredibly expensive and can be completely replaced by very inexpensive generic drugs and OTC products.

Herceptin is sold for $40,000 a year, while Genentech wants to charge $100,000 for Avastin. See the following Blog article for background information on Avastin, the cancer drug no one can afford.

http://grouppekurosawa.com/blog/2006/02/cancer-drugs-no-one-can-afford.htm

According to Genentech, 2005 sales of Avastin topped $1.182 billion. Herceptin sales were $764 million.

Avastin is an antibody that binds and neutralizes a blood vessel growth factor called VEGF or vascular endothelial growth factor. VEGF and other blood vessel growth factors promote angiogenesis or the growth of blood vessels. Tumors cannot grow beyond a certain small size unless they are constantly fed with new blood vessels and the nutrients that these blood vessels supply. If you block angiogenesis, cancer cells become unstable and subject to death. Avastin neutralizes VEGF AFTER it is made in tumor and other cells. It does NOT inhibit the production of VEGF in these cells. Avastin is only approved for use with chemotherapy drugs.

Herceptin is an antibody that binds the epidermal growth factor receptor HER2. The receptor is overexpressed in many breast and ovarian cancers, and promotes the survival of these cells. Herceptin is only approved for use with chemotherapy drugs.

In the following blogs, I am going to tell you why Genentech, in the next five years, is subject to total financial collapse. These two obscenely expensive drugs are unnecessary as they can be replaced by cheap generic drugs and OTC products.

I disclose that I own no stock in Genentech nor do I intend to take a "short" position in their stocks in the future. At one time, I absolutely loved and admired this company. But when they began financially gouging people with cancer, the rules changed. I am now officially pissed off.

Genentech, and companies like it, are one of the reasons our health care systems do not work. They make and distribute anti-cancer products that are affordable only to the rich or heavily insured. Granted, they do work to some extent, but they can be EASILY replaced by other products. And that is exactly what is going to happen. It is intolerable to relegate 45 million uninsured Americans and hundreds of millions of poor people around the world to deaths by cancer when cheap, effective drugs are available. We simply have to get the word out.

Stay tuned...

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com

US Healthcare. Most Expensive, Least Cost Effective

America, the richest country in the world, has a health care system that is the most expensive and least cost effective in the world. The reason? Well, pure greed is a start. But there are other problems.

In the last week, the news has been on the 25th anniversary of the HIV epidemic, and all the new cancer drugs in the pipeline.

I once read a story on the Net where a reporter referred to HIV scientists as the most arrogant group of people he had ever met. I guess he had never been around a bunch of oncologists. And I thought I had a big ego.

Ego aside, the problem with both HIV and cancer research is an inability to see the "little things". The "little thing" that interests me the most is the role of prostaglandins, such as PGE2, in the growth of cancer cells and development of various immune dysfunctions. When drugs such as ibuprofen and indomethacin, a powerful anti-inflammatory drug used to treat gout, can also be effectively used to treat chronic and acute diseases, you have to wonder why our health care costs are so high...and the treatment protocols so ineffective?

Because no one is listening. This information is all documented in the scientific literature, but there is no incentive to implement this information into current medical protocols. I know that HMO doctors are not allowed to vary their treatment protocols without fear of reprisal. It's sad because the patients are the ones that suffer. I will give you a great example, in a following Blog, of a very expensive cancer drug that can be completely replaced with ibuprofen or preferably indomethacin. That essay will shock and offend you.

Medicine in the US works less and less as the costs continue to increase. This is why so many people, including those with medical insurance, are flocking to alternative medicine practioners. Unfortunately, many of them are quacks, but that is another story.

These medical issues are discussed both in our Blog Archives and our current Natural Medicine Blog.

Stay tuned...

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com

The End of the Biotech Revolution. Six Weeks and Counting

You heard it here first. In six weeks, we will have conclusive evidence if one of our FREE treatment protocols works. If it does, this free protocol, and variations on it, will destroy the market share of ANY company that makes HIV, influenza, asthma, eczema and anti-allergy drugs. That's alot of companies.

Background.

Working with my devoted Kurosawa Mice, volunteers who adopt certain treatment procedures in an effort to validate natural medicine based medicinal protocols, I have confidence that at least some of our treatment protocols are working. The most notable example is the protocol for HIV infections. This protocol was formulated to specially rid the body of the HIV virus. In short, this protocol, unlike current HIV drug protocols, was designed to cure the disease.

The history of our efforts to "take out" the HIV virus can be found in the following document. This document describes our current HIV treatment protocol in detail. See our other Blogs for further documented information.

http://www.grouppekurosawa.com/hivprotocolprint.htm

What does this have to do with the end of the biotech revolution?

Simply put, everything.

Our primary HIV Mouse adopted the current HIV treatment protocol about 4-5 weeks ago. In addition to HIV, he also suffered from asthma and eczema. Both of these diseases were caused by the immune defect induced by HIV viral proteins. In the last two weeks, his asthma and eczema have disappeared. This means his immune system has readjusted itself. The protocol works.

In six weeks, we will have his blood test results. This test will tell us if his HIV count has indeed decreased while his CD4 T cell count increased.

This is the issue. The immune system is very complex. In the lymphocyte cell population, there are two groups of cells. The first group are called alpha beta T cells and they constitute the majority of the lymphocytes in the body. The second group are called gamma delta T cells and they constitute less than 10% of the T lymphocytes in the body. There is now substantial evidence that gamma delta T cells may be the dominant or most important T cells in the body. Our HIV treatment protocol was designed to block HIV induced immunosuppression, caused largely by excessive protaglandin release, and to activate gamma delta T cells. We believe this protocol succeeded.

In the alpha beta population of cells, CD4 T cells are divided into two populations. The first is TH1 dominant. This group of T cells promotes cell mediated immunity against cancer cells and virally infected cells. The second group is TH2 dominant. This group of cells promotes antibody based immunity by secreting immune hormones such as IL-4, IL-5, and IL-13.

A TH2 dominant immune response is characteristic of HIV and other viral infections, including influenza and hepatitis.  Other diseases, such as asthma, eczema, and all allergies are also characterized by a TH2 dominant immune response. This type of immune response makes these diseases WORSE.  If this TH2 immune response can be shifted to a TH1 dominant response, most of these diseases will either disaappear on their own or be eliminated by the immune system.

The issue of a TH2 over a TH1 immune response to allergens, viruses/pathogens, pollutants, and cancer cells is a subject of Biblical Importance. Do not minimize the importance of my words. We have developed a treatment protocol that is FREE, costs little to implement and does not require medical care. And the SAME protocol works on an almost endless number of diseases.

Sounds too good to be true? So was the collapse of the Berlin Wall and the Soviet Block of nations. But they happened.

In the next Blogs, I will discuss biotech and pharmaceutical companies whose products will be maximally adversely affected by this new FREE immunological protocol. I do not own any stocks whatsoever nor do I communicate the content of my blogs before they are written and published. I am simply a scientist reporting the facts.

Stay tuned...

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com

Gossip From France

I have some dear friends from France who I've worked with for a number of years. The woman, Cat, has breast cancer but has successfully battled it with a combination of chemo and natural medicines.

When they are asked by friends for the secret of their success, they tell them. They purchase specific supplements and take them with the chemo drugs. This enhances the efficacy of the chemo protocol.

France and most other European countries have socialized medicine programs. If a person purchases drugs, they are reimbursed by the government. But they are not reimbursed for the purchase of supplements. 

Here is the irony. These people will not follow Cat's successful breast cancer treatment protocol because it means they have to purchase the supplements "out of pocket". Their very lives could be at stake, but they refuse to spend a few extra dollars to insure that the "approved" treatment protocol works more effectively.

It reminds me of that old Jack Benny joke. He had a reputation for being very cheap.

"Your money or your life", the robber shouted. Benny said nothing.

"I said your money or your life. Didn't you hear me?"

"I'm thinking", Benny answered.

If people in Europe think their socialized medical treatment protocols are going to cure their cancers, they had better seriously reevaluate their situation.

I am not against socialized medicine. I think its fine. But current cancer treatment protocols do not work very well. Blocking chemo resistance with natural medicines and supplements is the easiest thing in the world. Europeans, like Americans and Canadians, are going to have to pay for these natural medicines and supplements out of their pocket or they risk a fairly nasty cancer related death.

I am completely serious.

Stay tuned...

Grouppe Kurosawa, Medicine in the Public Interest

http://www.grouppekurosawa.com